Treatments

Traditionally, opioid derivatives drugs are used to treat severe migraine crisis

Migraña

Medicinal Properties of Cannabinoids, Terpenes, and Flavonoids in Cannabis, and Benefits in Migraine, Headache, and Pain: An Update on Current Evidence and Cannabis Science. (2018)

Abstract

Comprehensive literature reviews of historical perspectives and evidence supporting cannabis/cannabinoids in the treatment of pain, including migraine and headache, with associated neurobiological mechanisms of pain modulation have been well described. Most of the existing literature reports on the cannabinoids Δ9 -tetrahydrocannabinol (THC) and cannabidiol (CBD), or cannabis in general[…]

Author Information

Baron EP.

Department of Neurology, Center for Neurological Restoration – Headache and Chronic Pain Medicine, Cleveland Clinic Neurological Institute, Cleveland, OH, 44195, USA.

Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis cohort. (2018)

Abstract

Medicinal cannabis registries typically report pain as the most common reason for use. It would be clinically useful to identify patterns of cannabis treatment in migraine and headache, as compared to arthritis and chronic pain, and to analyze preferred cannabis strains, biochemical profiles, and prescription medication substitutions with cannabis[…]

Author Information

Baron EP, Lucas P, Eades J, Hogue O.

Center for Neurological Restoration – Headache and Chronic Pain Medicine, Department of Neurology, Cleveland Clinic Neurological Institute, 10524 Euclid Avenue, C21, Cleveland, OH, 44195, USA. barone2@ccf.org. Tilray, 1100 Maughan Rd, Nanaimo, BC, V9X 1J2, Canada. Social Dimensions of Health, University of Victoria, 3800 Finnerty Rd, Victoria, BC, V8P 5C2, Canada. Canadian Institute for Substance Use Research, 2300 McKenzie Ave, Victoria, BC, V8N 5M8, Canada. Section of Biostatistics, Department of Quantitative Health Sciences, Cleveland Clinic Lerner Research Institute, 9500 Euclid Avenue, JJN3, Cleveland, OH, 44195, USA.

Anti-migraine effect of ∆9-tetrahydrocannabinol in the female rat. (2018)

Abstract

Current anti-migraine treatments have limited efficacy and many side effects. Although anecdotal evidence suggests that marijuana is useful for migraine, this hypothesis has not been tested in a controlled experiment. Thus, the present study tested whether administration of ∆9-tetrahydrocannabinol (THC) produces anti-migraine effects in the female rat[…]

Author Information

Kandasamy R, Dawson CT, Craft RM, Morgan MM.

Graduate Program in Neuroscience, Washington State University, Pullman, WA, USA. Electronic address: ram_kandasamy@wsu.edu. Department of Psychology, Washington State University Vancouver, Vancouver, WA, USA. Department of Psychology, Washington State University, Pullman, WA, USA; Translational Addiction Research Center, Washington State University, Pullman, WA, USA. Graduate Program in Neuroscience, Washington State University, Pullman, WA, USA; Department of Psychology, Washington State University Vancouver, Vancouver, WA, USA; Translational Addiction Research Center, Washington State University, Pullman, WA, USA.

Clinical Endocannabinoid Deficiency Reconsidered: Current Research Supports the Theory in Migraine, Fibromyalgia, Irritable Bowel, and Other Treatment-Resistant Syndromes. (2016)

Abstract

Medicine continues to struggle in its approaches to numerous common subjective pain syndromes that lack objective signs and remain treatment resistant. Foremost among these are migraine, fibromyalgia, and irritable bowel syndrome, disorders that may overlap in their affected populations and whose sufferers have all endured the stigma of a psychosomatic label, as well as the failure of endless pharmacotherapeutic interventions with substandard benefit[…]

Author Information

Russo EB.

PHYTECS, Vashon Island, Washington.

Effects of Medical Marijuana on Migraine Headache Frequency in an Adult Population. (2016)

Abstract

One hundred twenty-one adults with the primary diagnosis of migraine headache who were recommended migraine treatment or prophylaxis with medical marijuana by a physician, between January 2010 and September 2014, and had at least one follow-up visit[…]

Author Information

Rhyne DN, Anderson SL, Gedde M, Borgelt LM.

Department of Clinical Pharmacy, University of Colorado Anschutz Medical Campus Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado. Gedde Whole Health, Littleton, Colorado. Department of Family Medicine, University of Colorado Anschutz Medical Campus School of Medicine, Aurora, Colorado.

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