Treatments

CBD is known to be an anti-inflammatory agent

ENFERMEDADES CARDIOVASCULARES

Cannabinoids in the Cardiovascular System. (2017)

Abstract

Cannabinoids are known to modulate cardiovascular functions including heart rate, vascular tone, and blood pressure in humans and animal models. Essential components of the endocannabinoid system, namely, the production, degradation, and signaling pathways of endocannabinoids have been described[…]

Author Information

Ho WSV, Kelly MEM.

Vascular Biology Research Centre, St George’s University of London, London, United Kingdom. Electronic address: vho@sgul.ac.uk. Dalhousie University, Halifax, NS, Canada.

Cardiovascular effects of marijuana and synthetic cannabinoids: the good, the bad, and the ugly. (2018)

Abstract

Dysregulation of the endogenous lipid mediators endocannabinoids and their G-protein-coupled cannabinoid receptors 1 and 2 (CB1R and CB2R) has been implicated in a variety of cardiovascular pathologies. Activation of CB1R facilitates the development of cardiometabolic disease, whereas activation of CB2R (expressed primarily in immune cells) exerts anti-inflammatory effects[…]

Author Information

Pacher P, Steffens S, Haskó G, Schindler TH, Kunos G.

Laboratory of Cardiovascular Physiology and Tissue Injury, National Institutes of Health/NIAAA, 5625 Fishers Lane, Bethesda, Maryland 20892, USA. Institute for Cardiovascular Prevention, Ludwig-Maximilians-University and German Centre for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Pettenkoferstrasse 8a und 9b, Munich, D-80336, Germany. Department of Surgery, Rutgers New Jersey Medical School, 185 South Orange Avenue, Newark, New Jersey 07103, USA. Department of Radiology, Johns Hopkins University, 601 North Caroline Street, Baltimore, Maryland 21287, USA. Laboratory of Physiological Studies, National Institutes of Health/NIAAA, 5625 Fishers Lane, Bethesda, Maryland 20892, USA.

Cannabinoids and Symptomatic Bradycardia. (2018)

Abstract

Cannabinoids, the bioactive components of marijuana, have adverse cardiovascular consequences, including symptomatic sinus bradycardia, sinus arrest and ventricular asystole. Physicians should be aware of these deleterious consequences which can appear in otherwise healthy persons who are chronic marijuana users[…]

Author Information

Heckle MR, Nayyar M, Sinclair SE, Weber KT.

Division of Cardiovascular Diseases. Division of Pulmonary, Critical Care, and Sleep Medicine, University of Tennessee Health Science Center, Memphis, Tennessee. Division of Cardiovascular Diseases. Electronic address: KTWeber@uthsc.edu.

Cannabinoids and inflammation: implications for people living with HIV. (2019)

Abstract

Thanks to the success of modern antiretroviral therapy (ART), people living with HIV (PLWH) have life expectancies which approach that of persons in the general population. However, despite the ability of ART to suppress viral replication, PLWH have high levels of chronic systemic inflammation which drives the development of comorbidities such as cardiovascular disease, diabetes and non-AIDS associated malignancies[…]

Author Information

Costiniuk CT, Jenabian MA.

Chronic Viral Illness Service, Division of Infectious Diseases, Department of Medicine, McGill University Health Centre, Montreal. Infectious Diseases and Immunity in Global Health Program, Research Institute of McGill University Health Centre. McGill Research Centre for Cannabis and the Mark Wainberg Centre for Viral Diseases. Department of Microbiology and Immunology, McGill University. Department of Biological Sciences, University of Quebec at Montreal (UQAM). Department of Microbiology, Infectiology and Immunology, Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada.

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